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GET TO KNOW YOUR NEIGHBOR ; SDEE 2015 Year End Social on Dec 8th in San Diego ; Must Attend 5-Day Event in San Diego Starting Tomorrow! -- CDW on Cells, Sensors, and Sysems, with Updates on Stem Cells ; SDEE October 2015 Event - Financings: Tales from the Tranches ; Allele Biotech Takes Major Step into Nano Antibody Leadership Position
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Where genome editing is needed
Wednesday, 01.27.2016, 12:02am
The journal endorses the principle of transparency in the production of genome-edited crops and livestock as a precondition for the registration of a breed or cultivar, with no further need for regulation or distinction of these goods from the products of traditional breeding.
Parkinson's disease: Disorder in the court
Wednesday, 01.27.2016, 12:02am
The native structure of the protein α-synuclein, which is implicated in Parkinson's disease, is controversial. In-cell nuclear magnetic resonance now shows that it remains disordered when loaded into living cells.
Bioresorbable silicon electronic sensors for the brain
Tuesday, 01.19.2016, 09:11pm
Here, we report materials, device architectures, integration strategies, and in vivo demonstrations in rats of implantable, multifunctional silicon sensors for the brain, for which all of the constituent materials naturally resorb via hydrolysis and/or metabolic action, eliminating the need for extraction. 
Highly multiplexed targeted DNA sequencing from single nuclei
Monday, 01.18.2016, 11:17pm
This single nucleus-targeted sequencing approach incorporates multiplexing and targeted capture for efficient high-throughput detection of genome variants. The protocol will be particularly useful for studying rare cells and complex cell populations.
Genetic code expansion in stable cell lines enables encoded chromatin modification
Monday, 01.18.2016, 11:16pm
Stable integration of genes that facilitate the incorporation of unnatural amino acids into the amber stop codon in genes of interest allows targeted integration of acetyl-lysine into histone H3.3 and the investigation of its effects in mouse embryonic stem cells.
Tropomyosin controls sarcomere-like contractions for rigidity sensing and suppressing growth on soft matrices
Monday, 01.18.2016, 11:16pm
Sheetz and colleagues use micropillar arrays to report that the regulation of rigidity sensing involves the tropomyosin-dependent control of the stepwise contractions needed to reach a force level sufficient for integrin adhesion reinforcement.
  » Back to the past in schizophrenia genomics
  » Xenotransplantation makes a comeback
  » Polarization modulation adds little additional information to super-resolution fluorescence microscopy
  » Cell biology: Lipid code for membrane recycling
  » [Report] Pulmonary neuroendocrine cells function as airway sensors to control lung immune response
  » CETP inhibitors boost 'good' cholesterol to no avail
  » Xenotransplantation makes a comeback
  » Points of View: Pathways
  » Measurement noise 100 times lower than the quantum-projection limit using entangled atoms
  » GFI1 proteins orchestrate the emergence of haematopoietic stem cells through recruitment of LSD1

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High quality histologic services are crucial for determining study outcomes.

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Confidence and certainty: distinct probabilistic quantities for different goals
EMPIAR: a public archive for raw electron microscopy image data
Enabling direct fate conversion with network biology
High-density three-dimensional localization microscopy across large volumes
A saposin-lipoprotein nanoparticle system for membrane proteins
Mycocerosic acid synthase exemplifies the architecture of reducing polyketide synthases
A saposin-lipoprotein nanoparticle system for membrane proteins
Conceptual and technical advances define a key moment for theoretical neuroscience
Points of View: Neural circuit diagrams
Stem cells in the limelight