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GET TO KNOW YOUR NEIGHBOR ; SDEE 2015 Year End Social on Dec 8th in San Diego ; Must Attend 5-Day Event in San Diego Starting Tomorrow! -- CDW on Cells, Sensors, and Sysems, with Updates on Stem Cells ; SDEE October 2015 Event - Financings: Tales from the Tranches ; Allele Biotech Takes Major Step into Nano Antibody Leadership Position
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iPSC MSC ESC Differentiation
Expression of microRNA clusters predicts differentiation propensity of hESCs or hiPSCs
Monday, 08.29.2011, 11:17am
How do you know if a stem cell line will differentiate well by a particular protocol?  Some miRNA levels may be the answer.
New from Yamanaka lab: "Master transcription factor" Glis1 promotes reprogramming
Wednesday, 06.22.2011, 05:56am
Glis1 promotes multiple pro-reprogramming pathways, including Myc, Nanog, Lin28, Wnt, Essrb and the mesenchymal–epithelial transition.
Pluripotency depends on cell-cell contact
Tuesday, 05.31.2011, 10:20am
If E-cadherin is removed, the stem cells lose their pluripotency.  If E-cadherin is added, Oct4 is not needed for making iPSCs.
Human neurons can be directly generated from somatic cells.
Friday, 05.27.2011, 09:23am
Brn2 (also known as Pou3f2), Ascl1, Myt1l, and NeuroD1 on lentivirus can induce neurons from human fibroblasts
Focus on stem cells
Thursday, 05.05.2011, 12:33pm
This issue presents a series of specially commissioned articles that highlight exciting facets of stem cell research, including recent insights into the nature of pluripotency and how studying stem cells can increase our understanding of normal ageing and disease.
Chemically defined conditions for human iPSC derivation and culture
Friday, 04.15.2011, 12:53pm
A defined and simplified culture system for the derivation and growth of human induced pluripotent stem cells is reported. It permits increased efficiency of human reprogramming with an episomal approach.
  » A bioinformatic assay for pluripotency in human cells by Müller et al.
  » Deubiquitylase HAUSP stabilizes REST and promotes maintenance of neural progenitor cells
  » Generation of Functional Heart Cells by Direct Programming
  » More Naïve State of Human iPSCs?
  » Oct3/4 Promoter Blocks Cancer Stem Cells from Differentiation—Potential for Stably Supplying CSCs
  » Mouse induced pluripotent stem cells (iPSCs) differ from embryonic stem cells with aberrant silencing of imprinted genes on chromosome 12qF1
  » Rebuilding a windpipe with own stemcells
  » Wnt/b-Catenin important for stem cells responsible for leukemia, but not needed in normal hematopoietic stem cells (HSC).
  » Blood vessels may be a new niche for stem cells
  » Sox2 and Oct4 are the “Master Regulators" of Stem Cells

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Allele Biotech's DNA-free, feeder-free, xeno-free mRNA reprogramming method is being applied to human clinical programs. Start your iPSC system right from the start!
::| Hot News
Enabling direct fate conversion with network biology
Stem cells in the limelight
Stem cells in the limelight
Regeneration: Stem cells make the bowel nervous
Dystrophin expression in muscle stem cells regulates their polarity and asymmetric division
Distinct regulatory mechanisms governing embryonic versus adult adipocyte maturation
Generation of stomach tissue from mouse embryonic stem cells
Hepatic progenitor cells of biliary origin with liver repopulation capacity
Automated, high-throughput derivation, characterization and differentiation of induced pluripotent stem cells
XBP1, a determinant of the eosinophil lineage