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GET TO KNOW YOUR NEIGHBOR ; SDEE 2015 Year End Social on Dec 8th in San Diego ; Must Attend 5-Day Event in San Diego Starting Tomorrow! -- CDW on Cells, Sensors, and Sysems, with Updates on Stem Cells ; SDEE October 2015 Event - Financings: Tales from the Tranches ; Allele Biotech Takes Major Step into Nano Antibody Leadership Position
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Using single cell technologies for functional studies
 
 
Highly multiplexed simultaneous detection of RNAs and proteins in single cells
Tuesday, 02.09.2016, 01:30am

PLAYR (proximity ligation assay for RNA) enables highly multiplexed transcript quantification in combination with protein marker detection in single cells using flow or mass cytometry.

 

Gene regulation: Expression feels two pulses
Tuesday, 10.20.2015, 09:44am
Single-cell analyses reveal that combinatorial changes in the intracellular locations of transcription factors can tune the expression of the factors' target genes in response to environmental stimuli.
Gene regulation: Expression feels two pulses
Thursday, 10.15.2015, 08:38pm
Single-cell analyses reveal that combinatorial changes in the intracellular locations of transcription factors can tune the expression of the factors' target genes in response to environmental stimuli.
Robust enumeration of cell subsets from tissue expression profiles
Friday, 04.10.2015, 12:16pm
A computational method to identify cell types within a complex tissue, based on analysis of gene expression profiles, is described in this paper.
Evolution: Fitness tracking for adapting populations
Thursday, 02.26.2015, 11:02am
A method for tracking the descendants of hundreds of thousands of yeast cells in an evolving population reveals that thousands of individuals contribute to early increases in population-wide fitness.
Targeting cells with single vectors using multiple-feature Boolean logic
Wednesday, 06.11.2014, 11:12pm
This paper describes a single-vector strategy for flexible intersectional expression of genetically encoded reporters and tools in precisely defined cell types in the mouse.
Targeting cells with single vectors using multiple-feature Boolean logic
Monday, 06.09.2014, 09:46am
This paper describes a single-vector strategy for flexible intersectional expression of genetically encoded reporters and tools in precisely defined cell types in the mouse.
  » Single-cell western blotting
  » [Report] Highly Multiplexed Subcellular RNA Sequencing in Situ
  » Determining cell division symmetry through the dissection of dividing cells using single-cell expression analysis
  » Single-cell technologies for monitoring immune systems
  » Structural and functional analysis of single neurons to correlate synaptic connectivity with grooming behavior
  » One in a thousand: defining the limits of olfactory perception
  » Quantitative assessment of single-cell RNA-sequencing methods
  » Image-based transcriptomics in thousands of single human cells at single-molecule resolution
  » Multicolor multicycle molecular profiling with quantum dots for single-cell analysis
  » Single cell techniques isolated resident T cells in asymptomatic Herpes infection


 
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High quality histologic services are crucial for determining study outcomes. http://www.allelebiotech.com/histology/

::| Hot News
Highly multiplexed simultaneous detection of RNAs and proteins in single cells
Robust enumeration of cell subsets from tissue expression profiles
Evolution: Fitness tracking for adapting populations
Targeting cells with single vectors using multiple-feature Boolean logic
Single-cell western blotting
[Report] Highly Multiplexed Subcellular RNA Sequencing in Situ
Determining cell division symmetry through the dissection of dividing cells using single-cell expression analysis
Single-cell technologies for monitoring immune systems
Structural and functional analysis of single neurons to correlate synaptic connectivity with grooming behavior
Quantitative assessment of single-cell RNA-sequencing methods