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GET TO KNOW YOUR NEIGHBOR ; SDEE 2015 Year End Social on Dec 8th in San Diego ; Must Attend 5-Day Event in San Diego Starting Tomorrow! -- CDW on Cells, Sensors, and Sysems, with Updates on Stem Cells ; SDEE October 2015 Event - Financings: Tales from the Tranches ; Allele Biotech Takes Major Step into Nano Antibody Leadership Position
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Imaging, Structure, and Optogenetics
 
Glycine receptor mechanism elucidated by electron cryo-microscopy
Tuesday, 09.08.2015, 02:45pm
A high-resolution electron cryo-microscopy structure of the zebrafish α1 glycine receptor bound to agonists or antagonists reveals the conformational changes that take place when the channel transitions from closed to open state.
Inverse four-wave mixing and self-parametric amplification in optical fibre
Friday, 08.28.2015, 06:55pm
Self-parametric amplification, a nonlinear optical effect, is observed in optical fibre and results in optical spectrum narrowing and stable propagation.
ChR2 coming of age
Wednesday, 08.26.2015, 11:16am
10 years ago, channelrhodopsin-2 was expressed in neurons and shown to control their activity. In this issue, we consider how the field has developed since these early optogenetic experiments.
Super-resolution links vinculin localization to function in focal adhesions
Wednesday, 07.29.2015, 08:50pm
The combination of three-dimensional super-resolution imaging and loss- or gain-of-function protein mutants now links the nanoscale dynamic localization of proteins to their activation and function within focal adhesions.
Imaging G protein–coupled receptors while quantifying their ligand-binding free-energy landscape
Wednesday, 07.29.2015, 08:50pm
A force-distance curve–based atomic force microscopy method is developed and applied to both image and quantify the ligand-binding free-energy landscape of single protease-activated receptor-1 (PAR1) molecules under physiologically relevant conditions.
Single-molecule spectroscopy of protein conformational dynamics in live eukaryotic cells
Wednesday, 07.22.2015, 11:17am
Individual protein dynamics can be studied in live eukaryotic cells from the millisecond to nanosecond level using an integrated approach to confocal single-molecule FRET spectroscopy.
  » Probing ultrafast photo-induced dynamics of the exchange energy in a Heisenberg antiferromagnet
  » Computational high-resolution optical imaging of the living human retina
  » Quantitative evaluation of software packages for single-molecule localization microscopy
  » Preparation of compact biocompatible quantum dots using multicoordinating molecular-scale ligands based on a zwitterionic hydrophilic motif and lipoic acid anchors
  » Independent and coordinate trafficking of single Drosophila germ plasm mRNAs
  » High-performance probes for light and electron microscopy
  » Single-beam spectrally controlled two-dimensional Raman spectroscopy
  » Myosin-II-mediated cell shape changes and cell intercalation contribute to primitive streak formation
  » Myosin-II-mediated cell shape changes and cell intercalation contribute to primitive streak formation
  » Structural biology: Pain-sensing TRPA1 channel resolved


 
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High quality histologic services are crucial for determining study outcomes. http://www.allelebiotech.com/histology/
::| Hot News
EMPIAR: a public archive for raw electron microscopy image data
High-density three-dimensional localization microscopy across large volumes
Mycocerosic acid synthase exemplifies the architecture of reducing polyketide synthases
A saposin-lipoprotein nanoparticle system for membrane proteins
Fabrication of nanopores with ultrashort single-walled carbon nanotubes inserted in a lipid bilayer
High-power sub-two-cycle mid-infrared pulses at 100 MHz repetition rate
SR-Tesseler: a method to segment and quantify localization-based super-resolution microscopy data
Super-resolution links vinculin localization to function in focal adhesions
Single-molecule spectroscopy of protein conformational dynamics in live eukaryotic cells
Computational high-resolution optical imaging of the living human retina