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GET TO KNOW YOUR NEIGHBOR ; SDEE 2015 Year End Social on Dec 8th in San Diego ; Must Attend 5-Day Event in San Diego Starting Tomorrow! -- CDW on Cells, Sensors, and Sysems, with Updates on Stem Cells ; SDEE October 2015 Event - Financings: Tales from the Tranches ; Allele Biotech Takes Major Step into Nano Antibody Leadership Position
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NexGen Sequencing, Epigenetics, and Editing
A map of rice genome variation reveals the origin of cultivated rice
Wednesday, 10.03.2012, 02:51pm
Whole-genome sequences of wild rice and cultivated rice varieties are used to produce a map of rice genome variation, and show that rice was probably first domesticated in southern China.
A metagenome-wide association study of gut microbiota in type 2 diabetes
Friday, 09.28.2012, 09:25am
The authors have developed a new method, metagenome-wide association study (MGWAS), to compare the combined genetic content of the faecal microbiota of healthy people versus patients with type 2 diabetes; they identify multiple microbial species and metabolic pathways that are associated with either cohort and show that some of these may be used as biomarkers.
Incomplete methylation reprogramming in SCNT embryos
Tuesday, 09.18.2012, 07:44am
The cloning of Dolly the sheep was a remarkable demonstration of the oocyte's ability to reprogram a specialized nucleus. However, embryos derived from such somatic cell nuclear transfer (SCNT) very rarely result in live births—a fate that may be linked to observed epigenetic defects. A new genome-wide study shows that epigenetic reprogramming in SCNT embryos does not fully recapitulate the natural DNA demethylation events occurring at fertilization, resulting in aberrant methylation at some promoters and repetitive elements that may contribute to developmental failure.
Oxford Nanopore announcement sets sequencing sector abuzz
Thursday, 04.12.2012, 09:43am
The MinION generated particular excitement as a memory key–sized disposable unit that can be plugged into a laptop for under $1,000, according to the company.
Building a better sequence alignment program
Tuesday, 04.03.2012, 08:48am
When Langmead fed Bowtie 2 a couple of million HiSeq Illumina sequencing reads, its default settings could align those reads in 12 minutes. The next-fastest alignment tool took 32 minutes.
Disposable sequencer based on pulling DNA through nanopores
Thursday, 02.23.2012, 12:16pm
"The systems rely on nanopore sequencing, a method for reading long, unbroken strands of DNA and RNA. A proprietary enzyme pulls the strands through specially engineered nanopores in a polymer membrane" as reported in BioTechnique
  » Next-generation sequencing to generate interactome datasets

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::| Hot News
Analysis of five years of controlled access and data sharing compliance at the International Cancer Genome Consortium
Analysis of computational footprinting methods for DNase sequencing experiments
Mammalian NET-seq analysis defines nascent RNA profiles and associated RNA processing genome-wide
Co-occurrence of MYC amplification and TP53 mutations in human cancer
Quantification of private information leakage from phenotype-genotype data: linking attacks
Improving databases for human variation
A diamond in the ruff
Microbiomes: Curating communities from plants
Small island, big genetic discoveries
TARDIS, a targeted RNA directional sequencing method for rare RNA discovery