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GET TO KNOW YOUR NEIGHBOR ; SDEE 2015 Year End Social on Dec 8th in San Diego ; Must Attend 5-Day Event in San Diego Starting Tomorrow! -- CDW on Cells, Sensors, and Sysems, with Updates on Stem Cells ; SDEE October 2015 Event - Financings: Tales from the Tranches ; Allele Biotech Takes Major Step into Nano Antibody Leadership Position
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NexGen Sequencing, Epigenetics, and Editing
 
Taking pan-cancer analysis global
Thursday, 10.31.2013, 09:48am
Although federated cooperation is politically desirable, uniform data quality and standards are essential and should not be reinvented from scratch. The International Cancer Genome Consortium (ICGC) will do well to start with the data standards of The Cancer Genome Atlas (TCGA) and the Pediatric Cancer Genome Consortium if it is to succeed in genomic analysis across cancer types.
Taking pan-cancer analysis global
Tuesday, 10.29.2013, 08:58am
Although federated cooperation is politically desirable, uniform data quality and standards are essential and should not be reinvented from scratch. The International Cancer Genome Consortium (ICGC) will do well to start with the data standards of The Cancer Genome Atlas (TCGA) and the Pediatric Cancer Genome Consortium if it is to succeed in genomic analysis across cancer types.
Accounting for technical noise in single-cell RNA-seq experiments
Wednesday, 09.25.2013, 08:48am
A statistical method that uses spike-ins to model the dependence of technical noise on transcript abundance in single-cell RNA-seq experiments allows identification of genes wherein observed variability in read counts can be reliably interpreted as a signal of biological variability as opposed to the effect of technical noise.
MiTCR: software for T-cell receptor sequencing data analysis
Thursday, 09.12.2013, 09:24am
The approaches MiTCR uses to analyze TCR sequencing data have been shown to be efficient in previous studies. The software performs CDR3 extraction, identifies V, D and J segments, assembles clonotypes, filters out or rescues low-quality reads and provides advanced correction of PCR and sequencing errors.
Oxidative bisulfite sequencing of 5-methylcytosine and 5-hydroxymethylcytosine
Tuesday, 09.10.2013, 10:38am
To uncover the function of and interplay between the mammalian cytosine modifications 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC), new techniques and advances in current technology are needed. To this end, we have developed oxidative bisulfite sequencing (oxBS-seq), which can
Conserved Regulation of Cardiac Calcium Uptake by Peptides Encoded in Small Open Reading Frames
Friday, 08.23.2013, 12:51am
Small Open Reading Frames (smORFs) are short DNA sequences able to encode small peptides of less than 100 amino acids.Want to know what they do?
  » Specific elimination of mutant mitochondrial genomes in patient-derived cells by mitoTALENs
  » Turning off Down’s syndrome genes by silencing extra chromosome
  » CRESTing the ALS mountain
  » Comprehensive molecular characterization of clear cell renal cell carcinoma
  » Mutational heterogeneity in cancer and the search for new cancer-associated genes
  » Million veterans sequenced
  » Genomics: A gut prediction
  » Exploring long-range genome interactions using the WashU Epigenome Browser
  » Comparative analysis of RNA sequencing methods for degraded or low-input samples
  » Genomes can be lean and mean


 
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::| Hot News
Analysis of five years of controlled access and data sharing compliance at the International Cancer Genome Consortium
Analysis of computational footprinting methods for DNase sequencing experiments
Mammalian NET-seq analysis defines nascent RNA profiles and associated RNA processing genome-wide
Co-occurrence of MYC amplification and TP53 mutations in human cancer
Quantification of private information leakage from phenotype-genotype data: linking attacks
Improving databases for human variation
A diamond in the ruff
Microbiomes: Curating communities from plants
Small island, big genetic discoveries
TARDIS, a targeted RNA directional sequencing method for rare RNA discovery