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GET TO KNOW YOUR NEIGHBOR ; SDEE 2015 Year End Social on Dec 8th in San Diego ; Must Attend 5-Day Event in San Diego Starting Tomorrow! -- CDW on Cells, Sensors, and Sysems, with Updates on Stem Cells ; SDEE October 2015 Event - Financings: Tales from the Tranches ; Allele Biotech Takes Major Step into Nano Antibody Leadership Position
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NexGen Sequencing, Epigenetics, and Editing
 
Cancer: Damage prevention targeted
Thursday, 04.03.2014, 10:02am
The MTH1 protein prevents oxidized nucleotides from being misincorporated into DNA. Two studies find that selective inhibition of MTH1 by small molecules suppresses tumour growth.
Diversity and dynamics of the Drosophila transcriptome
Tuesday, 03.18.2014, 09:29pm
A large-scale transcriptome analysis in Drosophila melanogaster, across tissues, cell types and conditions, provides insights into global patterns and diversity of transcription initiation, splicing, polyadenylation and non-coding RNA expression.
Genome-wide identification and quantification of protein synthesis in cultured cells and whole tissues by puromycin-associated nascent chain proteomics (PUNCH-P)
Monday, 03.10.2014, 06:07pm
Regulation of mRNA translation has a pivotal role in modulating protein levels, and the genome-wide identification of proteins synthesized at a given time is indispensable to our understanding of gene expression.
Cell biology: Stressful genetics in Crohn's disease
Thursday, 02.20.2014, 10:39am
A common variant of the autophagy protein ATG16L1 is a risk factor for Crohn's disease. But the genetic alteration is revealed only when the protein is cleaved by the enzyme caspase 3 during cellular stress.
Standards for clinical use of genetic variants
Tuesday, 02.04.2014, 12:00pm
The price of DNA sequencing has never been lower. However, there is little consensus as to when the identification of a genetic variant is clinically useful.
Standards for clinical use of genetic variants
Thursday, 01.30.2014, 11:11am
The price of DNA sequencing has never been lower. However, there is little consensus as to when the identification of a genetic variant is clinically useful.
  » Similarity network fusion for aggregating data types on a genomic scale
  » Mapping Argonaute and conventional RNA-binding protein interactions with RNA at single-nucleotide resolution using HITS-CLIP and CIMS analysis
  » The cancer epigenome of mice and men
  » Sequenom falls after judge invalidates Down's patent
  » Discovery and saturation analysis of cancer genes across 21 tumour types
  » Sequencing: End-to-end RNA sequencing
  » Archaic humans: Four makes a party
  » [Report] Genome-Scale CRISPR-Cas9 Knockout Screening in Human Cells
  » [Report] Genome-Scale CRISPR-Cas9 Knockout Screening in Human Cells
  » Newborns sequenced at NIH


 
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::| Hot News
Analysis of five years of controlled access and data sharing compliance at the International Cancer Genome Consortium
Analysis of computational footprinting methods for DNase sequencing experiments
Mammalian NET-seq analysis defines nascent RNA profiles and associated RNA processing genome-wide
Co-occurrence of MYC amplification and TP53 mutations in human cancer
Quantification of private information leakage from phenotype-genotype data: linking attacks
Improving databases for human variation
A diamond in the ruff
Microbiomes: Curating communities from plants
Small island, big genetic discoveries
TARDIS, a targeted RNA directional sequencing method for rare RNA discovery