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Tuesday, 01.23.2018, 02:54pm (GMT-7)
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GET TO KNOW YOUR NEIGHBOR ; SDEE 2015 Year End Social on Dec 8th in San Diego ; Must Attend 5-Day Event in San Diego Starting Tomorrow! -- CDW on Cells, Sensors, and Sysems, with Updates on Stem Cells ; SDEE October 2015 Event - Financings: Tales from the Tranches ; Allele Biotech Takes Major Step into Nano Antibody Leadership Position
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NexGen Sequencing, Epigenetics, and Editing
 
Digenome-seq: genome-wide profiling of CRISPR-Cas9 off-target effects in human cells
Wednesday, 02.11.2015, 11:03am
In vitro digestion of genomic DNA with Cas9 and single guide RNAs (sgRNAs) yields genome-wide off-target sites at frequencies below 0.1%. Off-target sites can be further reduced with modified sgRNAs.
Growing access to phenotype data
Wednesday, 02.11.2015, 12:48am
Plant genomes are the index that will allow plant breeders and researchers to access the information contained in the world's seed banks, with each allele linking germplasm, genotype and phenotype.
Growing access to phenotype data
Friday, 02.06.2015, 04:17pm
Plant genomes are the index that will allow plant breeders and researchers to access the information contained in the world's seed banks, with each allele linking germplasm, genotype and phenotype. The journal endorses the international DivSeek initiative and will work with authors to ensure access to phenotype data linked to published genetic data.
A genome to unveil the mysteries of orchids
Tuesday, 01.27.2015, 03:21pm
Orchids have captured imaginations worldwide for hundreds of years. The publication of the moth orchid genome sequence opens the door to a greater understanding of orchid morphological evolution and physiological adaptation.
qPMS9: An Efficient Algorithm for Quorum Planted Motif Search
Thursday, 01.15.2015, 11:06am
We study the (ℓ, d) motif search problem or Planted Motif Search (PMS). PMS receives as input n strings and two integers ℓ and d. It returns all sequences M of length ℓ that occur in each input string, where each occurrence differs from M in at most d positions. Another formulation is quorum PMS (qPMS), where the motif appears in at least q% of the strings.
Pseudomonas aeruginosa adaptation to human hosts
Tuesday, 01.13.2015, 03:15pm
Bacterial whole-genome sequencing of longitudinally collected isolates enables the investigation of evolutionary trajectories, which may inform both the prevention and treatment of human-associated pathogen infections. A new study explores the adaptation of multiple lineages of Pseudomonas aeruginosa to the lungs of young patients with cystic fibrosis and finds evidence of convergent molecular evolution and historical contingencies.
  » Genomic and metabolic analysis of fluoranthene degradation pathway in Celeribacter indicus P73T
  » Pseudomonas aeruginosa adaptation to human hosts
  » A shared architecture for promoters and enhancers
  » Genomics: African dawn
  » Human Genome Variation
  » Predicting the human epigenome from DNA motifs
  » Detecting ultralow-frequency mutations by Duplex Sequencing
  » Genomics: Of monarchs and migration
  » Rapid editing and evolution of bacterial genomes using libraries of synthetic DNA
  » Diagnostic value of circulating free DNA for the detection of EGFR mutation status in NSCLC: a systematic review and meta-analysis


 
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::| Hot News
Analysis of five years of controlled access and data sharing compliance at the International Cancer Genome Consortium
Analysis of computational footprinting methods for DNase sequencing experiments
Mammalian NET-seq analysis defines nascent RNA profiles and associated RNA processing genome-wide
Co-occurrence of MYC amplification and TP53 mutations in human cancer
Quantification of private information leakage from phenotype-genotype data: linking attacks
Improving databases for human variation
A diamond in the ruff
Microbiomes: Curating communities from plants
Small island, big genetic discoveries
TARDIS, a targeted RNA directional sequencing method for rare RNA discovery