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GET TO KNOW YOUR NEIGHBOR ; SDEE 2015 Year End Social on Dec 8th in San Diego ; Must Attend 5-Day Event in San Diego Starting Tomorrow! -- CDW on Cells, Sensors, and Sysems, with Updates on Stem Cells ; SDEE October 2015 Event - Financings: Tales from the Tranches ; Allele Biotech Takes Major Step into Nano Antibody Leadership Position
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Immune systems, T cell Therapy, stem cell therapy
 
Alopecia areata is driven by cytotoxic T lymphocytes and is reversed by JAK inhibition
Thursday, 08.21.2014, 10:22am
Cytotoxic T cells are necessary and sufficient for the development of alopecia areata in mice, while JAK inhibition promotes regrowth of hair in patients and mice with established disease.
CAR-T cell therapy seeks strategies to harness cytokine storm
Monday, 07.28.2014, 12:13pm
A grading scheme to predict toxicity to chimeric antigen receptor T (CAR-T) cell therapies published on May 29 is a bold attempt to manage one of the most promising immunotherapy approaches to fight cancer.
cASCading specks
Friday, 07.25.2014, 10:00am
Inflammasome-driven inflammation extends into the extracellular space and to neighboring cells through the passive release of specks consisting of the adaptor ASC; this perpetuates the innate immune response and adds a dimension beyond interleukin 1 to autoinflammation.
New ingredients for brewing CD4+T (cells): TCF-1 and LEF-1
Monday, 07.14.2014, 02:28pm
The transcription factors TCF-1 and LEF-1 have diverse roles in differentiation into the CD4+ lineage through means both dependent on and independent of the transcription factor Th-POK.
New ingredients for brewing CD4+T (cells): TCF-1 and LEF-1
Monday, 06.30.2014, 02:16pm
The transcription factors TCF-1 and LEF-1 have diverse roles in differentiation into the CD4+ lineage through means both dependent on and independent of the transcription factor Th-POK.
New ingredients for brewing CD4+T (cells): TCF-1 and LEF-1
Friday, 06.27.2014, 09:29am
The transcription factors TCF-1 and LEF-1 have diverse roles in differentiation into the CD4+ lineage through means both dependent on and independent of the transcription factor Th-POK.
  » New ingredients for brewing CD4+T (cells): TCF-1 and LEF-1
  » Tumorigenicity and genetic profiling of circulating tumor cells in small-cell lung cancer
  » Noncoding RNA and its associated proteins as regulatory elements of the immune system
  » Noncoding RNA and its associated proteins as regulatory elements of the immune system
  » Modifying immunity
  » SGK1: master and commander of the fate of helper T cells
  » Hybrid recreation by reverse breeding in Arabidopsis thaliana
  » [Report] A Thylakoid-Located Two-Pore Potassium Channel Controls Photosynthetic Light Utilization in Plants
  » Contrary to popular belief--about GM food
  » Making fuel from engineered bacteria


 
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::| Hot News
Stem cells in the limelight
The genomic landscape of adult T cell leukemia/lymphoma
Reversed-polarity Treg cell TCRs provide a shock
Reversed-polarity Treg cell TCRs provide a shock
Subversion of anticancer immunosurveillance by radiotherapy
[Report] Genomic correlates of response to CTLA4 blockade in metastatic melanoma
CD47 blockade triggers T cell–mediated destruction of immunogenic tumors
CD8+ T cell diversification by asymmetric cell division
CD47 blockade triggers T cell–mediated destruction of immunogenic tumors
DPP4 in anti-tumor immunity: going beyond the enzyme