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GET TO KNOW YOUR NEIGHBOR ; SDEE 2015 Year End Social on Dec 8th in San Diego ; Must Attend 5-Day Event in San Diego Starting Tomorrow! -- CDW on Cells, Sensors, and Sysems, with Updates on Stem Cells ; SDEE October 2015 Event - Financings: Tales from the Tranches ; Allele Biotech Takes Major Step into Nano Antibody Leadership Position
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Immune systems, T cell Therapy, stem cell therapy
 
 
Stem cells in the limelight
Saturday, 03.05.2016, 03:04am

Stem cell biology has emerged as one of the most exciting areas of basic and biomedical research. This month, we launch a series of specially commissioned articles that discuss recent advances and challenges in this field.

 

Reflections on immunological nomenclature: in praise of imperfection
Wednesday, 02.17.2016, 11:14pm
The immunological community is faced with important challenges related to nomenclature at a time of genomic landscaping and single-cell analysis.
Decoding the immune response to successful influenza vaccination
Monday, 02.01.2016, 11:45pm
Systems immunology identifies molecular and cellular signatures associated with adverse clinical events and antibody response to a vaccine against H1N1 influenza virus.
The development and maintenance of resident macrophages
Monday, 12.28.2015, 04:39pm
Gomez Perdiguero and Geissmann discuss the origin of tissue macrophages as a layered system composed of resident macrophages originating mostly from yolk-sac progenitor cells and transitory myeloid cells that originate and renew from bone marrow hematopoietic stem cells.
The genomic landscape of adult T cell leukemia/lymphoma
Friday, 11.20.2015, 01:00am
Adult T cell leukemia/lymphoma (ATL) is a neoplasm linked to human T-lymphotropic virus type-1 (HTLV-1) infection and is refractory to current combination chemotherapy. A large genomic and transcriptomic study of ATL now provides detailed insight into the molecular lesions implicated in the development of this T cell malignancy.
Reversed-polarity Treg cell TCRs provide a shock
Wednesday, 11.04.2015, 10:38am
Docking of T cell antigen receptors (TCRs) engaging complexes of peptide and major histocompatibility complex has shown the same diagonal orientation and polarity. A new study demonstrating that TCRs from regulatory T cells bind with reversed polarity challenges this dogma.
Reversed-polarity Treg cell TCRs provide a shock
Wednesday, 10.28.2015, 10:13am
Docking of T cell antigen receptors (TCRs) engaging complexes of peptide and major histocompatibility complex has shown the same diagonal orientation and polarity. A new study demonstrating that TCRs from regulatory T cells bind with reversed polarity challenges this dogma.
  » Reversed-polarity Treg cell TCRs provide a shock
  » PAR1 signaling regulates the retention and recruitment of EPCR-expressing bone marrow hematopoietic stem cells
  » [Report] Tissue residency of innate lymphoid cells in lymphoid and non-lymphoid organs
  » Subversion of anticancer immunosurveillance by radiotherapy
  » Immunology: Caspase target drives pyroptosis
  » [Report] Genomic correlates of response to CTLA4 blockade in metastatic melanoma
  » CD47 blockade triggers T cell–mediated destruction of immunogenic tumors
  » CD8+ T cell diversification by asymmetric cell division
  » CD47 blockade triggers T cell–mediated destruction of immunogenic tumors
  » XBP1, a determinant of the eosinophil lineage


 
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::| Hot News
Stem cells in the limelight
The genomic landscape of adult T cell leukemia/lymphoma
Reversed-polarity Treg cell TCRs provide a shock
Reversed-polarity Treg cell TCRs provide a shock
Subversion of anticancer immunosurveillance by radiotherapy
[Report] Genomic correlates of response to CTLA4 blockade in metastatic melanoma
CD47 blockade triggers T cell–mediated destruction of immunogenic tumors
CD8+ T cell diversification by asymmetric cell division
CD47 blockade triggers T cell–mediated destruction of immunogenic tumors
DPP4 in anti-tumor immunity: going beyond the enzyme