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GET TO KNOW YOUR NEIGHBOR ; SDEE 2015 Year End Social on Dec 8th in San Diego ; Must Attend 5-Day Event in San Diego Starting Tomorrow! -- CDW on Cells, Sensors, and Sysems, with Updates on Stem Cells ; SDEE October 2015 Event - Financings: Tales from the Tranches ; Allele Biotech Takes Major Step into Nano Antibody Leadership Position
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Camelid Antibodies
 
 
Dpp spreading is required for medial but not for lateral wing disc growth
Tuesday, 11.10.2015, 11:40am

The morphogen Decapentaplegic (Dpp) has been implicated in both wing patterning and growth in fruitflies; here, a nanobody-based morphotrap approach has been developed that rules out a role for the Dpp gradient in regulating lateral wing growth.

 

Complementary IMAC enrichment methods for HLA-associated phosphopeptide identification by mass spectrometry
Friday, 08.28.2015, 06:55pm
Determining the phosphorylation of low-abundance peptides in small amount of clinical samples is challenging. In this approach, in-house construction of IMAC columns plus esterification of the peptides are the key features that improve sensitivity.
Allele Biotech Takes Major Step into Nano Antibody Leadership Position
Wednesday, 08.26.2015, 11:09am
The nAb product line will shortly encompass a wide range of high value targets that are applicable to both basic and clinically relevant research. It will also feature cutting edge conjugation technologies that enable fluorescent imaging and electron microscopy techniques being developed at Allele.
Assessment of a method to characterize antibody selectivity and specificity for use in immunoprecipitation
Wednesday, 07.01.2015, 09:16am
A quantitative mass spectrometry–based standard operating procedure to classify antibody performance in immunoprecipitation is assessed in a multilaboratory study.
Protein binder woes
Thursday, 04.30.2015, 08:57am
The biology research landscape is littered with antibodies that perform poorly for many applications. Two publicly funded academic efforts to explore high-quality binder generation are coming to an end. What have we learned—and what happens next?
A robust pipeline for rapid production of versatile nanobody repertoires
Monday, 11.03.2014, 02:07pm
This paper presents an efficient method for generating nanobodies with high affinity and high specificity. In addition, a collection of nanobodies specific for GFP or mCherry that resulted from this work is described.
HIV immunity goes direct
Thursday, 05.08.2014, 09:06am
The commencement of human trials of a gene therapy delivering HIV-neutralizing antibodies is a welcome addition to efforts to develop conventional vaccines against this scourge.
  » Serum Helicobacter pylori NapA antibody as a potential biomarker for gastric cancer
  » Site-specific chemical modification of antibody fragments using traceless cleavable linkers
  » Into the wild: digging at immunology's evolutionary roots
  » Mouse platforms jostle for slice of humanized antibody market
  » A roadmap to generate renewable protein binders to the human proteome
  » Something new under the skin
  » GFP-Trap Successfully Used in Plants and Other Systems
  » Two affinity peptides linked as high affinity binders as “Synbody”
  » Immunoprecipitation Using GFP-Trap Identified Missing Structure-Specific Nucleases for DNA Repair in Human
  » Intracellularly Expressed Camelid Single-Domain Antibody (VHH) Counteracts Cytotoxicity Seen in Agricultural Epidemics


 
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For the past few years, Allele has been in the forefront of Camelid antibody technology offering popular products such as the GFP-Trap, now replaced with the new GFP-nAb product line with lower cost, higher binding capacity and spin column format.
http://www.allelebiotech.com/nab
::| Hot News
Dpp spreading is required for medial but not for lateral wing disc growth
Allele Biotech Takes Major Step into Nano Antibody Leadership Position
Assessment of a method to characterize antibody selectivity and specificity for use in immunoprecipitation
Protein binder woes
HIV immunity goes direct
Serum Helicobacter pylori NapA antibody as a potential biomarker for gastric cancer
Site-specific chemical modification of antibody fragments using traceless cleavable linkers
Into the wild: digging at immunology's evolutionary roots