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GET TO KNOW YOUR NEIGHBOR ; SDEE 2015 Year End Social on Dec 8th in San Diego ; Must Attend 5-Day Event in San Diego Starting Tomorrow! -- CDW on Cells, Sensors, and Sysems, with Updates on Stem Cells ; SDEE October 2015 Event - Financings: Tales from the Tranches ; Allele Biotech Takes Major Step into Nano Antibody Leadership Position
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Brain and Neuron Development
Focus on big data
Friday, 10.31.2014, 11:17am
Nature Neuroscience presents a special focus issue highlighting big data efforts under way in the field.
Cell-based reporters reveal in vivo dynamics of dopamine and norepinephrine release in murine cortex
Monday, 10.27.2014, 03:17pm
Cell-based reporters for dopamine and norepinephrine allow real-time measurements of these neurotransmitters in vivo with high specificity. They can address the temporal and spatial dynamics of volume neurotransmission in behaving animals.
Cleavage of tau by asparagine endopeptidase mediates the neurofibrillary pathology in Alzheimer's disease
Thursday, 10.23.2014, 09:21am
Tau cleavage and aggregation, key processes in many neurodegenerative diseases, can be reduced by blocking the activity of a protease called asparagine endopeptidase.
A touching tale: point sensor or pattern detector?
Monday, 10.20.2014, 11:10am
The tactile sensors in our fingers have variable sensitivity across the skin. Does this variability harm or help the CNS in touch perception? Work now shows that this variability may provide the CNS with more information about micropositioning and stimulus orientation.
A three-dimensional human neural cell culture model of Alzheimer’s disease
Tuesday, 10.14.2014, 08:59pm
Here we report that mutations in β-amyloid precursor protein and presenilin 1 are able to induce robust extracellular deposition of amyloid-β, including amyloid-β plaques, in a human neural stem-cell-derived three-dimensional (3D) culture system.
Neuroscience: Towards unified vesicle endocytosis
Thursday, 10.09.2014, 01:16pm
An ultrafast, temperature-dependent mode of endocytosis, a process that is required for neurons to repeatedly fire, challenges current thinking and brings an old model back into the spotlight.
  » A touching tale: point sensor or pattern detector?
  » Progranulin protects against amyloid β deposition and toxicity in Alzheimer's disease mouse models
  » Progranulin protects against amyloid β deposition and toxicity in Alzheimer's disease mouse models
  » Subcellular localization of coagulation factor II receptor-like 1 in neurons governs angiogenesis
  » Subcellular localization of coagulation factor II receptor-like 1 in neurons governs angiogenesis
  » The mythical brain
  » Soluble neuregulin-1 modulates disease pathogenesis in rodent models of Charcot-Marie-Tooth disease 1A
  » Resting-sate functional reorganization of the rat limbic system following neuropathic injury
  » The mythical brain
  » Something wicked this way comes: huntingtin

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::| Hot News
Confidence and certainty: distinct probabilistic quantities for different goals
Conceptual and technical advances define a key moment for theoretical neuroscience
Points of View: Neural circuit diagrams
Neurodevelopment: Regeneration switch is a gas
The peptidergic control circuit for sighing
Natural killers in the brain's nursery
Parkinson's disease: Disorder in the court
Bioresorbable silicon electronic sensors for the brain
Back to the past in schizophrenia genomics
Back to the past in schizophrenia genomics