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GET TO KNOW YOUR NEIGHBOR ; SDEE 2015 Year End Social on Dec 8th in San Diego ; Must Attend 5-Day Event in San Diego Starting Tomorrow! -- CDW on Cells, Sensors, and Sysems, with Updates on Stem Cells ; SDEE October 2015 Event - Financings: Tales from the Tranches ; Allele Biotech Takes Major Step into Nano Antibody Leadership Position
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Brain and Neuron Development
 
Genetic Risks to Nicotine Dependence Predict Negative Mood and Affect in Current Non-Smokers
Tuesday, 03.31.2015, 12:47pm
We found that nicotine administration led to the change of both measurement construct and factor means, indicating the causal effect of nicotine on the psychological responses.
Reversing excitatory GABAAR signaling restores synaptic plasticity and memory in a mouse model of Down syndrome
Thursday, 03.19.2015, 10:34am
Both chronic and acute treatment of adult Ts65Dn mice with the FDA-approved NKCC1 inhibitor bumetanide suppressed aberrant excitatory GABAAR signaling and rescued synaptic plasticity deficits and cognitive disabilities in this mouse model of Down syndrome.
Huntingtin facilitates selective autophagy
Wednesday, 03.18.2015, 09:18pm
Selective autophagy is essential for maintaining cellular homeostasis under different growth conditions. Huntingtin, mutated versions of which have been implicated in Huntington disease, is now shown to act as a scaffold protein that couples the induction of autophagy and the selective recruitment of cargo into autophagosomes.
Focal embolic cerebral ischemia in the rat
Tuesday, 03.17.2015, 01:25am
The middle cerebral artery (MCA) is occluded with a fibrin-rich allogeneic clot, producing an embolic model of MCA occlusion in the rat that mimics the key components of neurovascular damage observed in human ischemic stroke.
Focal embolic cerebral ischemia in the rat
Monday, 03.09.2015, 10:50pm
In this model, the middle cerebral artery (MCA) is occluded with a fibrin-rich allogeneic clot, producing an embolic model of MCA occlusion in the rat that mimics the key components of neurovascular damage observed in human ischemic stroke.
Neuroscience: Hot on the trail of temperature processing
Thursday, 03.05.2015, 10:49pm
Two studies investigate how information about temperature is processed in the brains of fruit flies, and reveal that different neuronal pathways transmit heating and cooling signals to higher brain regions.
  » Focus on epilepsy
  » Neuroscience: The cortical connection
  » Imagine a journey through time and space
  » Neurodegeneration: Cold shock protects the brain
  » Permanent genetic memory with>1-byte capacity
  » Attentional flexibility in the thalamus: now we're getting SOMwhere
  » Nature Neuroscience celebrates its 200th issue
  » Combination of mild hypothermia with neuroprotectants has greater neuroprotective effects during oxygen-glucose deprivation and reoxygenation-mediated neuronal injury
  » Direct cell–cell contact with the vascular niche maintains quiescent neural stem cells
  » In vivo imaging of oligodendrocytes with sulforhodamine 101


 
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::| Hot News
Confidence and certainty: distinct probabilistic quantities for different goals
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