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GET TO KNOW YOUR NEIGHBOR ; SDEE 2015 Year End Social on Dec 8th in San Diego ; Must Attend 5-Day Event in San Diego Starting Tomorrow! -- CDW on Cells, Sensors, and Sysems, with Updates on Stem Cells ; SDEE October 2015 Event - Financings: Tales from the Tranches ; Allele Biotech Takes Major Step into Nano Antibody Leadership Position
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Brain and Neuron Development
 
Treatment during a vulnerable developmental period rescues a genetic epilepsy
Wednesday, 12.16.2015, 02:37am
Treatment with the common diuretic bumetanide during a susceptible developmental window prevents epileptogenesis in a mouse model of a genetic epileptic encephalopathy.
Backward reasoning the formation rules
Monday, 12.07.2015, 02:27pm
Synaptic plasticity during learning is as fundamental as it is hard to study. The underlying synaptic plasticity rule has now been inferred using only the firing rate statistics of visual neurons in monkeys before and after learning.
Thalamus controls recurrent cortical dynamics
Thursday, 12.03.2015, 01:02am
Previous work has suggested that cortical recurrent circuits can self-sustain their activity without thalamic input. A study now demonstrates that this is not the case in the awake brain, which tightly locks cortical timing to thalamic activity.
Parkinson's disease–associated mutant VPS35 causes mitochondrial dysfunction by recycling DLP1 complexes
Tuesday, 12.01.2015, 03:03pm
Mutations in VPS35 that are associated with Parkinson's disease increase the interaction of VPS35 with mitochondrial DLP1, leading to removal of the DLP1 complexes and mitochondrial fragmentation. Structural and functional mitochondrial impairments caused by mutant VPS35 are observed in vitro using cultured neurons and fibroblasts from individuals with PD and in vivo in mouse substantia nigra neurons, where they induce neurodegeneration.
Neuroscience: A digital piece of brain
Tuesday, 10.27.2015, 05:54pm
Developments in automated sample preparation, electron microscopy and data analysis enable in-depth characterization of a chunk of mouse neocortex.
Neuroscience: A digital piece of brain
Thursday, 10.22.2015, 09:25pm
Developments in automated sample preparation, electron microscopy and data analysis enable in-depth characterization of a chunk of mouse neocortex.
  » Focus on stress
  » Parkinson's disease: Crystals of a toxic core
  » The binding solution?
  » Neutrophils promote Alzheimer's disease–like pathology and cognitive decline via LFA-1 integrin
  » Photovoltaic restoration of sight with high visual acuity
  » Multispectral labeling technique to map many neighboring axonal projections in the same tissue
  » Conceptualization and validation of an open-source closed-loop deep brain stimulation system in rat
  » High-resolution whole-brain staining for electron microscopic circuit reconstruction
  » High-resolution whole-brain staining for electron microscopic circuit reconstruction
  » Sugar and Alzheimer's disease: a bittersweet truth


 
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::| Hot News
Confidence and certainty: distinct probabilistic quantities for different goals
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Back to the past in schizophrenia genomics
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